Keep my session open?
Ending In 
The session is expired
A sua sessão expirou. Para sua segurança, fechámos a sua sessão.
Gostaria de reiniciar sessão?
Nova Sede a partir de 24/04! - Rua da Indústria nº6, Alfragide

Anti-Survivin Rabbit Polyclonal Antibody

Fornecedor: Thermo Scientific
For IHC, prior antigen retrieval (pressure cooking) is recommended for cytoplasmic and nuclear detection of Survivin. Suggested positive control: Hela whole cell extract, antigen standard for BIRC5 (transient overexpression lysate). Regulated inhibition of programmed cell death (apoptosis) preserves normal homeostasis and tissue and organ morphogenesis. Aberrations in this process contribute to human diseases and cancer by abnormally prolonging cell viability. Recently, several apoptosis inhibitors related to the baculovirus iap gene have been found in various species, including human. IAP proteins contain one/three Cys/His baculovirus IAP repeats plus a c-terminus RING finger and are thought to block an evolutionary conserved step in apoptosis. Survivin encodes a structurally unique inhibitor of apoptosis (IAP). Survivin expression is turned off during fetal development and is not found in non-neoplastic adult human tissues. Survivin becomes abundantly re-expressed in transformed cells and in all of the most common cancers of lung, colon, pancreas, breast and prostate in vivo. Survivin appears to be situated at the crossroads of cell death and cell division, governing a checkpoint involved in cytokinesis while also suppressing apoptosis. Survivin is also abundantly expressed in brain tissues (astrocytes and some neurons) of adult rats following traumatic brain injury. Survivin has been found co-expressed with NeuN (mature neuronal marker) and PCNA (a cell cycle protein). Survivin might affect regulation of neural cell proliferative responses after brain injury.

Type: Primary
Antigen: Survivin
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Rat, Mouse, Canine, Feline, Guinea Pig, Hamster, Human



Faça Login na página para visualizar o seu preço e disponibilidade dos artigos.
  Lembrar-me neste dispositivo
 

ENCOMENDA

Expandir tudo / Esconder tudo
Tamanho Und. Referência VWR Quantidade
100 µL 50 µl PIEAPA116836 Blocked
Blocked Este produto está bloqueado. Para obter mais informações, contacte a VWR através do número 213 600 770.
Gerar códigos de barras Barcode Label Format: 
Criar página do catálogo em PDF

ESPECIFICAÇÕES

Antigen symbol Survivin
Antigen name Baculoviral IAP Repeat Containing 5
Reactivity Mouse, Human, Guinea Pig, Rat, Hamster, Feline, Dog
Conjugation Unconjugated
Clonality Polyclonal
Antibody type Primary
Host Rabbit
Isotype IgG
Western Blot Yes
ELISA Yes
ImmunoChemistry Yes
ImmunoPrecipitation Yes
ImmunoFluorescence Yes
Flow Cytometry Yes
ChIP Yes
Antigen synonyms IAP4, EPR 1, Apoptosis inhibitor survivin, Baculoviral IAP repeat containing 5, Apoptosis Inhibitor 4, BIRC 5, API4, TIAP, SVV
Gene ID 332, 493835, 442936, 64041, 11799
Concentração 1 mg/ml
Immunogen Recombinant human survivin, full-length.
Purification Antigen affinity chromatography
Form Liquid
Storage Buffer PBS, 0.02% sodium azide
Temperatura de armazenamento -20°C or -80°C if preferred
Shipping Temperature Ice
Detalhes

Selecione o artigo para o qual procura o Certificado

Indique o número do lote. Este campo é obrigatório.

Inserir detalhes do certificado

Produto:

Número de Lote:

Choose from recent batch/lot numbers:

Ou
Review & Compare Alternatives
We found alternative products that can save you up to  per item-unit.  To compare product details, select up to 3 alternatives below and click Compare Selected. To add items to your basket, enter a quantity and click Add to Basket.

Original Product:

Descrição Código de Artigo Disponibilidade Unidade O seu preço Preço por Qtd